Following a comprehensive clinical evaluation, NICE concluded that machine perfusion offers significant advantages over traditional static cold storage. By supplying an oxygenated solution to donor livers prior to surgery, the VitaSmart system facilitates better outcomes while maintaining cost-efficiency. The guidance, published under reference HTG780, positions this technology as a critical tool for surgeons managing deceased donor organs.
NICE Backs Routine NHS Funding for Liver Perfusion Technology
The National Institute for Health and Care Excellence has issued new guidance recommending the routine funding of ex-situ machine perfusion devices for liver transplants. This decision formally integrates Bridge to Life’s VitaSmart system into the National Health Service framework, aiming to improve graft survival rates and reduce post-surgical biliary complications.

Don Webber, CEO of Bridge to Life, described the recommendation as a pivotal moment for establishing hypothermic oxygenated perfusion as the new standard of care. This move aligns the UK with broader European clinical practices, providing a standardized pathway for hospitals to adopt the technology. For transplant centers, the shift promises to simplify operating room logistics and increase the viability of organs from extended-criteria donors. Rebbeca Sanabria Mateos, a consultant at University Hospitals Birmingham, noted that the funding ensures equitable access to perfusion tools, ultimately expanding the pool of usable donor organs.



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