The upcoming session centers on the challenge of translating parental Fab attributes into functional bispecific antibodies (bsAbs). By utilizing a 160-member bispecific library, researchers have generated a high-dimensional dataset that reveals exactly where linear additivity breaks down. This empirical evidence provides a clearer roadmap for identifying which traits transfer reliably and which liabilities only appear post-assembly.
Ginkgo Bioworks Expert to Unpack Bispecific Antibody Development Risks
The "Rule of Additivity" often fails when predicting how parental antibodies influence complex bispecific assembly. On July 20, 2026, Ammar Arsiwala of Ginkgo Datapoints will host a technical webinar detailing how systematic developability data can identify emergent liabilities before they derail the development of complex biologics.
Attendees will examine the correlations and decouplings between individual Fab-arm attributes and final bsAb performance. The presentation aims to equip researchers with a more nuanced strategy for flagging pairing risks and de-risking candidates earlier in the design process. The webinar is scheduled for 12pm EDT on July 20, 2026.
Comments (0)
No comments yet. Be the first!